"Mr. Wu, I read a report that 301 has begun to study the microelectrode under the hypothalamic fornix nucleus for the treatment of Alzheimer''s disease. I think the location of your microelectrode is also in the hypothalamic fornix nucleus..."


    The people who came to watch the operation were sent away. Several people from jianxie hospital returned to the ward. Zhou Guohui asked as he walked.


    "Director Zhou, you''re too polite." Wu Mian was stunned and said with a smile, "don''t call the teacher. You''re kidding me."


    "Alas." Zhou Guohui sighed, "those who reach are respected, and they should. After seeing your postoperative effect, I have a feeling that the patient can recover at least 70% of his function and memory after the strength of anesthesia has completely passed."


    "When I was in school, teacher Zhuang and you were classmates. You call me that. How can I go back to Concord in the future?" Wu Mian scratched his head and said.


    "It''s all small things." Zhou Guohui asked, "are you connected with 301?"


    "Yes, we have been in touch." Wu Mian nodded, "In 1985, Professor Turnbull used basal nuclear power stimulation to treat dementia. In this study, a 74 year old patient was stimulated with left basal nuclear power. It was found that deep brain stimulation of basal nucleus could improve the glucose metabolism function of ipsilateral temporal lobe and parietal lobe, but could not improve the cognitive function of patients. Therefore, this study was delayed for some time."


    "The delay was 23 years. Until 2008, Dr. hamani accidentally found that electrical stimulation of hypothalamic fornix nucleus can improve the memory of patients in his research on the treatment of obese patients. After a series of experiments, it was preliminarily determined that the effective target of deep brain electrical stimulation in the treatment of dementia is hypothalamic fornix nucleus."


    "In the phase I clinical trial, the hypothalamic fornix nucleus was electrically stimulated for half a year to one year in patients with mild to moderate dementia. The results showed that the electrical stimulation of this part could alleviate or improve the degree of cognitive decline and improve brain glucose metabolism."


    "Later, in 2011, Dr. Ponce conducted a clinical phase II trial on 42 patients with dementia. The early safety research results showed that DBS electrode implantation into hypothalamic fornix nucleus was safe and reliable in the treatment of dementia."


    "There are two difficulties that cannot be solved because it has not developed. The first is that the target of hypothalamic fornix nucleus is located below the lateral ventricle and in front of the third ventricle, and the implanted electrode must pass through the lateral ventricle.


    Because the head end of the implanted electrode is thicker and blunt than the microelectrode, after the microelectrode recording, the implanted electrode is easy to slide along the lateral ventricular wall when passing through the lateral ventricular wall, which affects the accuracy of the target. "


    "In 2013, the 301 research group solved this problem with trocar assisted puncture technology. The next difficulty is positioning. Two years ago, general medical produced signapioneer 3.0T magnetic resonance system, and DST surround matrix gradient system is a breakthrough technological innovation in the field of magnetic resonance in recent ten years, making accurate positioning possible."


    "Every technology is built from scratch, studied by countless people and built little by little." Wu Mian said with a smile. "I''m just part of solving the last problem, nothing."


    Nothing. These three words are light, but Zhou Guohui knows how much they weigh.


    "Teacher Wu, awesome!" Zhou Guohui sincerely praised.


    Wu Mian did not continue to talk with Zhou Guohui about his calling himself a teacher. He said too much, which was greasy and boring.


    Back in the ward, Gao Baixiang squatted in the ward, always observing the patient''s postoperative state.


    Because the ward of Neurology has not been established, we can only deal with it here in Gao Baixiang.


    The overall diagnosis and treatment process of jianxie hospital is not formal. The old driver drives a new car, and Wu Mian doesn''t care very much. The patient must be hospitalized in the Department of Neurology and surgery, and hire someone to talk about it.


    This is not true. Zhou Guohui "threw himself into the net" and took refuge from the imperial capital.


    Come, easy; want to go, difficult.


    Wu Mian, a chief physician, department director and vice chairman of the society of Neurology, such as Zhou Guohui, will never let him go. Now after seeing a patient treated for Alzheimer''s disease, he won''t go even if he is expelled in a short time.


    "Miss Wu." when Gao Boxiang saw Wu Mian coming back, he immediately stood up and said hello.


    "Well, you go and have a rest." Wu Mian smiled. "I''ll watch it here."


    The patient''s postoperative magnetic resonance imaging showed that the current conduction of the brain nerve bundle had spread widely. Zhou Guohui said that at least 70% of the function was not aimless.


    But the patient has been sleeping after general anesthesia, and he hasn''t woken up yet. Wu Mian doesn''t want to miss the first-hand information about the specific effect.


    Gao Baixiang also knows that he is not a professional neurologist, and recently, with the spread of free congenital heart disease surgery, more and more patients come to consult and hospitalize.


    Heart surgery is Gao Baixiang''s main battlefield. Coupled with mitral valve clamping with thoracic surgery, Gao Baixiang is also very busy.


    After seeing off the irrelevant people, Wu Mian sat beside Chu Zhixi and looked at the sleeping old man through the glass.


    Yuan Wei was a little nervous. The city government was deep. The muscles on his face were tight without a smile. His eyes narrowed into a seam and stared at ah Yi in the single room.


    "Mr. Yuan, don''t be so nervous," said Wu Mian. "Your vital signs are stable and you''ll wake up soon."


    "Dr. Wu." Yuan Wei rubbed his hands on his pants, and the two water stains were clear. "I also saw the MRI image. Although I don''t know medicine, I know it can be done by looking at the image."


    "Yes."


    "I''m worried that when ah Yi wakes up and sees me, what will she do if she cries? Will it cause arrhythmia? It''s not long after heart surgery... I''m a little regretful. I''ll stay here for another 20 days and let ah Yi adapt..."


    Yuan Wei nagged, completely losing the gloomy and cruel strength of the once underground leader. Like the families of ordinary patients, he expects the effect of the operation to exceed his expectations.


    On this point, people and people are the same and common.


    "There''s no problem with the heart," said Wu Mian. "Relevant examinations have been done before the operation, and there is little chance of complications. I don''t agree in principle if you don''t say you want to have the operation. The patient''s state is not good, you can''t be in any hurry."


    "Ha ha." Yuan Wei rubbed his hands. The old cocoons rubbed against each other and made a rustling sound, just like the wind blowing through the sand and stones on the beach.


    "I wish I could remember me," Yuan Wei said, looking at her. "I don''t have any relatives in the world. I''m used to cheating and thinking I''m invulnerable. When she gradually didn''t know me... Dr. Wu, you don''t know how regretful I was."


    "Originally I wanted to work hard outside to make ah Yi live a good life. I suffered a lot in the first half of my life, but I can''t do it in the future. But now I''m good, but ah Yi doesn''t remember anything. My heart is empty."


    Yuan Wei revealed his mind. As he was saying this, Wu Mian suddenly stood up and strode into the ward.